Synthetic Studies Toward 3- or 4-Substituded Piperidines

Autor: Hang-Yi Tai, 戴航儀
Rok vydání: 2012
Druh dokumentu: 學位論文 ; thesis
Popis: 100
Piperidine derivatives usually have a significant biological activity. This study is divided into two themes : ( 1 ) To synthesize different derivatives from 3-substituded piperidines under acidic condition and using ring closing metathesis. ( 2 ) To synthesize different derivatives from 4-substituded piperidines using diisobutylaluminium hydride ( DIBALH ) These noval synthetic methods are more direct and rapid synthetic approaches to the piperidine skeletons.
Databáze: Networked Digital Library of Theses & Dissertations