The Development and Trend of Collagen

Autor: Yu-lian Li, 李玉蓮
Rok vydání: 2011
Druh dokumentu: 學位論文 ; thesis
Popis: 99
Collagen is abundant protein in animal body. It has unique triple-helix structure, and important structural and functional effects in the organisms. Collagen is the major structural protein of extracellular matrix, which is related to congenital diseases. Older adult with reduction of fibroblast and collagen damage by glycation, free radicals, endopeptidase and enzymic intermolecular cross-linking, will produce wrinkles, arthritis, osteoporosis and other issues. The purified collagen still remain the important triple-helix structure and biological activity. It can be absorbed by human body naturally, has good biodegradability and biocompatibility in the human body. This thesis will be analysis and comparison the sources of artificially extracted collagen, including bovine, pig, chicken and fish, with other sources such as microorganism containing recombinant collagen. There are three major extraction methods to obtain, including chemical, enzyamatic and microbiological treatments. The purified product obtained from extraction is applied to medicine, functional food and cosmetics. As technology evolves and matures, academia and the industry increasingly attach importance to the application and economic benefits of collagen.
Databáze: Networked Digital Library of Theses & Dissertations