Bone regeneration on the acid-etched titanium with collagen/chitosan coating
| Autor: | Shao-wei Yang, 楊紹威 |
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| Rok vydání: | 2011 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 99 According to research, the short-term adhesion and long-term stability on surface of porous structural implants are much better than smooth ones. In this study, the surface were coated collagen/chitosan complex membrane in addition to surface porous structure. Collagen provided scaffold strength and accompanies a function that accelerated the differentiation of osteoblasts. Chitosan with the purpose of guiding bone tissue growth, hemoglutination, and antibacterial. The adhesion, proliferation, differentiation of osteoblasts on titanium implants were tested in vitro; the bone healing and new-bone formation around the implants after implanting the surface-modified Ti plates into animal bodies were discussed in vivo. We expect that the time of bone regeneration, the bone integration and bone healing around implants could be improve by the surface-modification treatment. Moreover, with the purpose that reduced the suffering of patients and shortened the bone healing time, we hope this treatment could be introduced to surgical or dental implants soon after. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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