The Neural Correlates of Auditory Language Processing between Chinese and Japanese and the Effects of Aging: A Preliminary Investigation Using fMRI
| Autor: | Mei-Yuan Lin, 林鎂媛 |
|---|---|
| Rok vydání: | 2010 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 99 The aim of this study was to investigate the patterns of cortical activation during auditory semantic processing using fMRI and the effects of aging on this network. We reviewed current research for cortical activation patterns of auditory semantic processing and summarized relevant neuroimaging models of aging that showed consistent compensatory pattern of age-related changes in brain activity. We first examined similarities and differences in auditory phonological and semantic processing between Chinese and Japanese language. Based on language networks from younger population, we then examined compensatory pattern for auditory semantic processing in healthy elderly participants. We applied functional MRI and ROI analysis to investigate the activation patterns of language-related regions in healthy young and old participants. Young Japanese participants showed greater activation in temporoparietal regions including left supramarginal gyrus and left dorsal portion of inferior gyrus compared to young Taiwanese participants during speech perception processing of their respective languages. Japanese and Chinese language elicited similar activity in the semantic network, especially in the angular gyrus, middle temporal gyrus and the ventral portion of inferior frontal gyrus. In terms of aging effects, elderly Japanese adults had decreased left superior temporal gyrus activation compared to the younger Japanese, suggesting an initial change in the semantic language network. In addition, a general slowing during semantic judgment associated with the volumetric decline was observed. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
|