Evaluation of the Ambulatory Care Costs and Drug Utilization of the Post-Renal Transplant Patients with the Taiwan NHI Claims Database

Autor: Eric Kin-Lap Lee, 李建立
Rok vydání: 2011
Druh dokumentu: 學位論文 ; thesis
Popis: 99
OBJECTIVES: Owing to the first-year ambulatory cost after transplantation generally considered as an indicator of the success of the transplantation surgery, in this thesis we attempted to evaluate the ambulatory care costs and drug utilization of the post-renal transplant patients with the Taiwan NHI claimed database. Firstly we proposed to conduct a pharmacoepidemiology study to examine the utilization and the expenditure for immunosuppressants among renal transplant recipients in order to estimate the growth of future costs under the Taiwan global budget system. Secondly, we will compare the total expenditure of the first year post-transplantation ambulatory health care and drugs used that attempted to provide evidence that the renal transplantation was less costly than hemodialysis. Lastly, we hope to evaluate the differences of the ambulatory health care costs and drug utilization of the first year post-renal transplantation between the patients who have had domestic and foreign renal transplant surgery. STUDY MATERIALS & DATA MANAGEMENT: For the study data, we used the Taiwan Longitudinal Health Insurance Database (2005), which contained all of the claims data from 1,000,000 beneficiaries who were randomly sampled from the Registry for Beneficiaries of the National Health Insurance Research Database, which includes approximately 25.68 million individuals, namely, 98% of the population in Taiwan. This database contains all the ambulatory, emergency, and hospitalization claims information and costs tracked back to 1997 and carried to 2006. All of the NHRI data were delivered as text files and the SPSS Chinese version 13.0 statistical program was used to transcribe them into working files for further analysis. MAJOR FINDINGS: The first-year post-transplantation drug costs and total health care costs of the kidney, heart, lung, liver, and other organ transplantations were evaluated and the drug expenditures were about 80% of the total health care cost except for the other specified organ transplant, i.e., bone marrow, wherein they were 60%. The mean differences between drug expenditures and total costs of various organ transplants were significant differences (p
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