Electrochemical Determination of Ketamine by Chemically Modified Screen Printed Carbon Electrode
| Autor: | Shi-Hang Lin, 林仕航 |
|---|---|
| Rok vydání: | 2010 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 98 A chemically modified screen-printed carbon electrode(modified SPCE) was developed for the electrochemical oxidation determination of ketamine (2-(2-chlorophenyl)-2 methyl aminocyclohexanone). With simple modification of SPCE by organic solvent, the modified SPCE showed great increment of sensitivity in the determination of ketamine in phosphate buffer solutions. The pH effects for the ketamine determination with modified electrode on peak current and peak potential were also investigated, which showed the pH dependence of both results. Several organic solvents as the modifier were tested and the results were compared. Under optimized conditions, the chemically modified SPCE showed good linear dynamic range between 5.0μM to 200μM, with detection limit of 3.15μM. The applications of chemically modified SPCE on the determination of ketamine added in soft drink were also demonstrated. In the results showed, DMF and its similar organic solvents as the modifier were great improve the sensitivity in the determination of ketamine. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
|