Menstruational change and climacteric symptoms in women with breast cancer receiving chemotherapy

Autor: Chia Ying Li, 李家瑩
Rok vydání: 2010
Druh dokumentu: 學位論文 ; thesis
Popis: 98
This study aimed to examine: (1) the chemotherapy induced change of menstruation in pre-menopausal women with breast cancer; and (2) the effect of menstrual change in the severity and distress of climacteric symptoms. Data from 84 patients were analyzed. The results showed that: (1) Seventy-five percent had experienced menstrual change and most of them (79.4%) did not recover after two years. (2) Older women tended to have higher chance to experience menstrual change. (3) In terms of change pattern, the severity of psychological symptoms is gradually decreased; the trend of psychological distress and physiological symptoms demonstrated U shape while the vasomotor and sexual symptoms are reversed U shape. Except psychological (severity) and sexual (severity and distress) symptoms, the trends of all other symptoms showed significant time effects. (4) Menstrual change had significant effect on change of the severity of sexual symptoms; the magnitude of increase and decrease in sexual symptom severity was larger in women experiencing menstrual disruption. This investigation can provide understanding on menstrual change and climacteric symptoms in breast cancer women undergoing chemotherapy.
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