Low-Frequency Ultrasound Phased Array System Design
| Autor: | Yi Hung Chen, 陳逸鴻 |
|---|---|
| Rok vydání: | 2008 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 96 Focused ultrasound has been proven to have potential for local and reversible blood-brain barrier disruption in recent years, thereby contains potential for macromolecular drugs delivery into brain tissue to perform targeting brain drug delivery for brain disorder treatment. Current available system all design frequency higher than 500 kHz in order to generate focus for ultrasonic thermal ablation purpose. However, operating frequency higher than 500 kHz encounters obstacle that the energy could be blocked by intact skull. The purpose of this study is to design one 64-channel ultrasound phased array system which operates at low frequency for blood-brain barrier disruption. The system include Field Programmable Gate Array (FPGA)/ Micro-controller based control kernel, 64-channel power-controlled driving module, multiple-channel power sensoring module, and one 48-channel hemispherical ultrasound phased array transducer. The novelty of the proposed design is that we proposed to employ the microcontroller unit and the field programmable gate array to serve as the main control unit for multiple channel signals. System performance testing includes output power testing, feedback power testing, acoustic pressure testing and ultrasound pressure measurements. Our results showed that the system can successfully generate ultrasonic focus, and the focal position can be scanned by controlling the relative phases of elements with output power monitoring. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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