Effects of Modified Constraint-induced Therapy and Placebo-controlled Rehabilitation in Patients with Chronic Stroke: A Comparative Study

Autor: Yueh-Tsen Chen, 陳玥岑
Rok vydání: 2007
Druh dokumentu: 學位論文 ; thesis
Popis: 95
Objective: To examine the effectiveness of modified constraint-induced therapy (mCIT) in comparison with placebo-controlled traditional rehabilitation (TR) on motor impairment, daily function and quality of life. Design: Two-group design, pre- and post-intervention measures, randomized controlled trial. Setting: 3 rehabilitation departments. Participants: Twenty-two chronic patients (at least 6 months post-onset) with unilateral stroke. Interventions: Patients received either mCIT or placebo-controlled traditional rehabilitation, with 2-hour treatment and restraint of the unaffected upper extremity (UE) for 3 weeks. Main Outcome Measures: Outcome measures included assessments in the body structure and function domain (the Fugl-Meyer Assessment, Graded Wolf Motor Function Test, and Action Research Arm Test and 9-hole Peg Test), the activity domain (FIM and Revised Nottingham Extended Activities of Daily Living Scale) and the participation domain (Stroke Impact Scale and Stroke Specific Quality of Life Scale) in the International Classification of Functioning, Disability and Health framework. Results: The average restraint time of the two groups was comparable, and the two groups had similar motor performance in affected extremity after intervention. However, the mCIT group exhibited greater recovery and sustained motor ability in affected UE. Participants in the mCIT group were more independent in basic ADL and mobility in community, and reported better quality of life after treatment especially in domains related to physical function. Conclusions: mCIT conferred therapeutic benefits on some aspects of motor performance, daily functioning, transition to community, and quality of life, even though both groups received constraint of equal intensity outside the therapy time.
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