Fabrication of a Passive Mixing Device with Herringbone Hydrogel Microstructure

Autor: Kai-Jie Huang, 黃楷傑
Rok vydání: 2007
Druh dokumentu: 學位論文 ; thesis
Popis: 95
Micro total analysis system (μ-TAS) shall shrink a laboratory to chip-size lab-on-a-chip. Miniaturization of an overall analytical process from sample preparation through reaction and separation to detection. The microfludic mixing is a key technique in micro total analysis system. Microscale mixers can be divided into two broad classifications - passive and active. Active mixers need to use external energy to enhance mixing efficiency, but it’s fabricated process were more complicated. Passive mixers do not require external energy, indicating that the mixing mainly depends on the channel geometry. This study show a passive micromixer using stimuli-responsive hydrogel material to fabricate structure in the microchannel. Hydrogels are three-dimensional cross-linked polymers and it’s characteristics influenced by crosslinker, solvent volume, exposure time and substrate. Hydrogel components were fabricated inside PDMS microchannels via direct photopatterning of a liquid phase. This study fabricated herringbone hydrogel microstructure in microchannel and the passive mixing device with hydrogel microstructure has good mixing effect than passive mixing device without hydrogel microstructure.
Databáze: Networked Digital Library of Theses & Dissertations