Autor:	楊智仁
Rok vydání:	2007
Druh dokumentu:	學位論文 ; thesis
Popis:	95 Various (heterocyclo)carbonyl mono-oxime esters of anthraquinone were synthesized, which exhibied ability for single-strand scission of DNA upon UV irradiation. Their structure–acitivity relationship was established, in which the most potent compound was anthraquinone O-9-(1,3-benothiazole-2-carbonyl)oxime. It can nick DNA at the concentration as low as 1.0 μM.
Databáze:	Networked Digital Library of Theses & Dissertations
Externí odkaz:	http://ndltd.ncl.edu.tw/handle/89289485288185794957 Zobrazit plný text záznamu