Determinants of vascular complications in patients with type 2 diabetes mellitus.
| Autor: | Lee Ming-Chen, 李明珍 |
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| Rok vydání: | 2006 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 94 Diabetes is the fourth leading cause of death in Taiwan. Diabetes vascular complications is one of the major causes of mortality among DM patients. The vascular complications may induce not only physical suffering among DM patients, but also severely influence their psychological and social function. The quality of life of these patients may be disrupted and the substantial healthcare expenses may increase. The subjects of this study were 140 type 2 diabetic patients, In order to identify vascular complications risk factors, along with other measurements including glucose, triglyceride (TG), retinopathy, heart rate and urine albumin were investigated. In addition, the effects of glycemic control and renal dysfunction on vascular complications risk factors were also studied. Methods of the study included Olympus AU-600,Indirect ophthalmoscope ID-1, photo slit lamp SL-7F and Holter-ECG MT-200. All diabetic patients were classified into glycemic control subgroups according to HbA1c, albuminuria subgroups based on urinaryalbumin to creatinine ratio（ACR）, retinopathy and heart rate. According to results, diabetic patients poor control group had higher levels of fasting blood sugar (FBS), triglyceride (TG), cholesterol and heart rate, than those in good controls. Diabetic patients with either microalbuminuria or macroalbuminuria had higher levels of fasting glucose, triglyceride (TG), cholesterol and heart rate, than those in good control group. Diabetic patients with retinopathy had higher levels of fasting glucose, triglyceride (TG), cholesterol and heart rate, than those in good control group. Diabetic patients with heart rate had higher levels of fasting glucose, triglyceride (TG), cholesterol and heart rate, than those in good control group. In conclusion, type 2 diabetic patients with poor glycemic control status, renal dysfunction, or retinopathy could increase the severity of vascular complications. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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