Electrochemical Synthetic Application of Bisflavanones

Autor: Tzu-Sheng-Chuang, 莊慈生
Rok vydání: 2005
Druh dokumentu: 學位論文 ; thesis
Popis: 94
Biflavonoids usually exist in natural plants. They were found to have some activities in hepatitis B virus, anti-cancer,anti-spasm, improving immunity. 6-Methoxyflavone were synthesized by Baker- Venkataraman Rearrangement. We tried to invesgate the factors which affect the electroorganic dimerization of 6-methoxyflavone was easily reduced by using electrochemical method to give two hydrodimers of 6,6’-dimethoxy-2,2’-biflavanone (racemate) and 6,6’-dimethoxy-2,2’- biflavanone (meso) and one reductive product of 6-methoxyfiavaanone. Their yields were dependent on the nature of electrodes, the kinds of supporting electrolytes and the reaction temperature. They were found to afford higher yields of 6,6’-dimethoxy-2,2’-biflavanone (racemate), 6,6’-dimethoxy-2,2’-biflavanone (meso) and 6-methoxyfiavaanone.(24.9﹪, 22.9﹪,and38.5﹪,respectively,) in the reaction condition of Pd(-)/C(+)-0.1MH2SO4/MeOH-20F/mol at 0℃
Databáze: Networked Digital Library of Theses & Dissertations