The Effects of Eight Weeks Intermittent Hypoxia on Glucose Tolerance and Skeletal Muscle Morphology
| Autor: | Ming-Chieh Wu, 吳明杰 |
|---|---|
| Rok vydání: | 2005 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 93 The present study was to investigate the effects of eight weeks intermittent hypoxia (14% O2) on glucose tolerance and skeletal muscle morphology. Twenty-one Sprague-Dawley rats were matched for weight and assigned into following 3 treatments: control (C), 1-hr hypoxia/day (O), and 8-hr hypoxia/day (E). The fiber types of soleus and plantaris muscle were determined using the mATPase(pH4.6) and SDH method, and capillary density was visualized using the AP method. Abdominal fat weight, Fasting blood glucose, fasting and postprandial serum insulin concentration in E group was significant lower than C group during the OGTT. The E group had a significantly increased percentage of Type IIa fiber and capillary density in soleus muscle than C group, whereas the fiber size of soleus muscle decreased. Significant correlations were found among fasting blood glucose(r=0.43, p |
| Databáze: | Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
|