Speciation analysis of triorganotin compounds by capillary electrophoresis - inductively coupled plasma-mass spectrometry
| Autor: | Chien-Wei Lu, 呂健瑋 |
|---|---|
| Rok vydání: | 2004 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 92 Capillary Electrophoresis (CE) has been widely used in separated chemistry because of its higher number of theoretical plates than Gas Chromatography and Liquid Chromatography. The high-resolution inductively coupled plasma mass spectrometer (HR-ICP-MS) takes advantages than traditional quadrupole ICP-MS in interference free determination of almost the whole periodic table in almost every matrix and lower detection limit (ppt). Some elements are significant interference by polyatomic ions and cannot be tested without using high mass resolution. The CE and HR-ICP-MS are complementary. But how to hyphenated the two instruments finely is critical point of the research. Organotin compounds (OTs) have extensively been used as antifouling agent in ship paints and as fungicides in agriculture and stabilizers in plastic industry over the past years. Speciation is of major interest in OTs analysis, since toxicity is strongly dependent on the species. In order to understand their biological effects and estimate their environmental influences, there is a need for the development and improvement of analytical techniques capable of determining OTs in both aqueous, environmental and biological samples. Our laboratory hyphenated CE and HR-ICP/MS and discussed some parameters of the system. Then, Using the CE to separate the triorganotin compounds, and discussed some analysis parameters, then determined the amounts of tin in HR-ICP-MS for different standards. Five kinds of triorganotin compounds were successfully separated by using a pH 4.6-100 mM acetate buffer within 6 minutes. Reproducibility of migration time and peak area was better than 1.76 and 2.68%, respectively. The limits of detection for various triorganotin compounds were in the range of 1.79-9.68 nM based on peak area. Samples of seawater were analyzed with the CE-ICP/MS combination. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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