Mechanical Property Difference of the Principal Compressive Region of Femoral Head between the Patients with Osteoarthritis and Osteoporosis

Autor: Shih-Sheng Sun, 孫施盛
Rok vydání: 2002
Druh dokumentu: 學位論文 ; thesis
Popis: 90
Osteoarthritis (OA) and osteoporotic (OP) femoral neck fracture are the common musculoskeletal disorders of elderly people. According to the clinical finding of OA hip is rarely seen together with a fractured neck of the femur. We make a series of biomechanical test to compare the mechanical properties of the femoral head between OA and OP groups. Seven primary OA femoral heads and 7 OP femoral heads were resected for arthroplasty. First, the bone mineral density (BMD) of each femoral head was measured by Dual X-ray aborptiometry (DXA). Two 1 cm3 cubic testing samples (along principal compressive group) were cut from each femoral head. Cubic testing samples were then loaded in uniaxial compression using a material testing system (Bionix 858; MTS system comp., eden prairie, USA). All samples were loaded in the superior-inferior direction to compare the difference of OA and OP of the biomechanical properties (included Young’s modulus, yield stress). The results showed that the biomechanical properties were significantly different between OA and OP (whether the Young’s modulus or the yielding stress). Besides, the bone density of OA group is also double than OP group. From biomechanical view, higher stiffness of femoral head (OA) may less able to absorb impact loads, thus lead to increase peak stresses in the cartilage. In the other hand, lower stiffness of femoral head (OP) may develop to bone fracture. These data support the hypothesis that higher femoral bone stiffness may be one of the factors to develop OA disease.
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