Regulation of α1-Acid Glycoprotein Gene by TIF1β
| Autor: | Chen, Ya-Ling, 陳雅鈴 |
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| Rok vydání: | 1997 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 85 Nuclear receptors (NRs) act as ligand-inducible transcription factors which regulate the expression of target genes upon binding to their cognate response elements. Their ligand- dependent activation function, AF-2, presumably acts on the basal transcription machinery through transcriptional mediators/ intermediary factors (TIFs). But the molecular mechanisms underlying transcriptional activation by NRs are still poorly understood, although intermediary factors (mediator) appear to be involved in mediating |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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