The characteristics of dietary pattern and copper╱ zinc level 、 copper related antioxidant enzymes in hypercholesterolemic subjects.
| Autor: | Hsu Ching-Yun, 許青雲 |
|---|---|
| Rok vydání: | 1993 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 81 Hypercholesterolemia has been shown to be a consequ- ence of dietary copper (Cu) deficiency in experime- ntal animals. There are several biochemical changes in Cu deficiency. We examined the lipid level, sup- eroxide dismutase(SOD), glutathione peroxidase(GSHPx), ceruloplasmin (Cp) and plasma Cu and Zn levels in hyperchoesterolemic subjects (N=23, TC ＞240 mg/dl)、 borderline-hypercholesterolemic subjects (N=31, 200 ≦TC＜ 240mg/dl) and control subjects (N=25,TC＜200mg /dl). Total cholesterol、TG and LDL-C levels appeared to be higher than normal in hypercholesterolemic pa- tients (p＜0.05). However,the SOD、Cp and Zn levels in hypercholesterolemic subjects didn't significantly differ from control. Hypercholesterolemic subjects had lower Cu level than control' s ( p＜0.05 ). As a result,lipids levels were not related to plasma Cu 、SOD and Cp among the three groups.Plasma GSHPx levels was positively correlated with SOD、Cp value in control subjects (r=0.40,r=0.45 p＜0.05), but no correlation in hypercholesterolemic subjects was found. Results of semiquantitative food frequency questio- nnaire (FFQ) showed that intake of fatty meat was higher in hypercholesterolemic subjects than control, but the intake of crude fiber of fruits and leafly -vegetable had significant reverse relationship(p ＜0.05). The score test of nutritional knowledge in hypercholesterolemic subjects were lower than the other two groups (p＜0.05). |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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