| Popis: |
Long bone fractures are a commonly occurring injury that often require surgery in order to repair the fracture site completely. Despite concerned efforts to avoid bacterial contamination during surgery, surgical site infections (SSI) continue to be a major clinical complication. The development of antibacterial biomaterials that are capable of preventing bacterial attachment while aiding in bone growth and repair could prove to be beneficial to the field. Bioactive glass is a known biomaterial that is capable of producing hydroxyapatite (HA), a naturally occurring material with a chemical structure closely resembling that of human bone. In addition to osteoconductive benefits, bioactive glasses can be formulated to provide specific therapeutic benefits. In this study, a bioactive glass series was synthesized in which silver (Ag), a known antibacterial agent, was incorporated. After grinding the glass to an optimal particle size |
