| Popis: |
Background: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder (FGID) that affects 10-20% of adults and adolescents worldwide. A connection has been identified between the consumption of some foods and an exacerbation of IBS symptoms. One nutrition therapy option for IBS is the low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet. A lack of data describing the mechanism of action of this dietary pattern has led to insufficient evidence to establish standard clinical guidelines regarding the use of the low-FODMAP diet in IBS. Objective: This study aims to define the duration of the low-FODMAP diet elimination phase for optimal symptom relief and the nutritional adequacy of the low-FODMAP diet. Methods: Subjects attended a low-FODMAP diet group education class and were instructed to follow the low-FODMAP diet for six weeks. Subjects completed an IBS-Symptom Severity Scale questionnaire (IBS-SSS) at baseline and weeks 2, 4, and 6. Subjects completed a three-day diet record at baseline and week 2. Dietary compliance was assessed through daily high-FODMAP food checklists. Results: A total of 35 participants enrolled in this study. Complete data was available for 14 (40%) participants. Incomplete data was available for 2 (6%) participants, and 19 (54%) dropped out of the study. 43% (15/35) participants were responders to the diet (a reduction 50 points in IBS-SSS), and 87% (13/15) of responders saw a clinical response after two weeks of the diet. There was a significant reduction in symptoms seen between baseline and week two (p75% of participants. 71% of participants reported non-compliance.Conclusion: Our findings support that a low-FODMAP diet elimination phase of two weeks is optimal for achieving symptom relief. The low-FODMAP diet leads to a nutritionally inadequate dietary pattern and must be monitored in future studies. The high dropout rate and poor dietary compliance reported in this study highlight the need to assess dietary compliance in future interventions to determine if a reduction in IBS-SSS is a result of dietary FODMAP concentration or placebo effect. |
