| Popis: |
It has been hypothesized that the use of veterinary antimicrobials in livestock populations may lead to an increase in bacterial resistance to these antimicrobials among both animals and humans. Additionally, the transfer of resistance genes among bacterial pathogens may result in increased risk of food-borne disease resulting from pathogens with reduced susceptibility to the antimicrobials commonly used to treat them. Our objective is to measure changes in antimicrobial susceptibility of fecal Escherichia coli between 2001 and 2011 on 16 Ohio dairy farms. We assessed the reduced susceptibility proportions (RSP) of the 17 select antimicrobials, excluding apramycin, included in the National Antimicrobial Resistance Monitoring System surveillance program. We also examined the difference in the reduced susceptibility index (RSI) for these 16 herds.Over a 2 year period (2001-2002) 9,253 fecal samples were collected via rectal palpation from cows on 42 Ohio dairy farms. In 2011 we returned to 16 of these same 42 herds and collected a composite sample of 400 fecal samples (25 samples from each of the 16 herds) using the same methods of collection as in the previous study period. Results of the RSP data shows an increase in resistance to 4 antimicrobials (Ampicillin, Cephalothin, Chloramphenicol and Sulfamethoxazole) and no significant change in resistance to the remaining 12 antimicrobials included in our study. |
