| Popis: |
The purpose of this prospective, randomized, double-blind study was to determine ibuprofen versus ibuprofen/acetaminophen usage for postoperative endodontic pain in symptomatic patients with a pulpal diagnosis of necrosis experiencing moderate-to-severe preoperative pain. Additionally, we recorded escape medication usage. Seventy-one adult patients presenting for emergency endodontic treatment with a symptomatic maxillary or mandibular tooth with a pulpal diagnosis of necrosis with a radiolucent area and moderate to severe pain participated in this study. The patients were randomly divided into two groups blinded to both the doctor and patient by random assignment and numerical coding. An emergency debridement of the tooth was completed with hand and rotary instrumentation. At the end of the appointment, the patients were given either 600 mg ibuprofen or 600 mg ibuprofen combined with 1000 mg acetaminophen (blinded to both the operator and patient). Patients also received a 6 day diary to be completed after anesthesia wore off and every morning for five days. Patients were asked to record pain and symptoms and the number of pain medications taken. Patients received escape medication if the study medication was not controlling their pain. Postoperative data was analyzed by Randomization Test and Step-down Bonferroni method of Holm. There were average decreases in pain levels and analgesic usage over time for the ibuprofen and ibuprofen/acetaminophen groups, but there was no statistically significant difference between the two groups for analgesic usage or escape medication usage. Approximately 20% of patients in both groups required escape medication. |
