The effect of pathogens on plant genome stability
| Autor: | Filkowski, Jody, University of Lethbridge. Faculty of Arts and Science |
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| Rok vydání: | 2004 |
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| Druh dokumentu: | Diplomová práce |
| Popis: | Resistance (R) genes, a key factor in determining the resistance of plants, have been shown often to be highly allelic entities existing in duplicated regions of the genome. This characteristic suggests that R-gene acquisition may have arisen through frequent genetic rearrangements as a result of transient, reduced genome stability. Tabacco plants transgenic for a recombination construct exhibited reduced genome stability upon infection with a virulent pathogen (tobacco mosaic virus). The reduced genome stability manifested as an increase in recombination events in the transgene. Such increases were observed following a virulent pathogen attack. This increase in recombination was shown to be systemic and was observed prior to systemic viral movement suggesting the presence of a systemic recombination signal. Further molecular analyses revealed that specific R-gene loci experience a large frequency of rearrangements following a virulent pathogen encounter. The possible targeting of instability to R-gene regions may be controlled through epigenetic processes, in particular, DNA methylation. xiii, 119 leaves ; 29 cm. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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