Reconsidering Gender Relative to Risk of Rupture in the Contemporary Management of Abdominal Aortic Aneurysms

Autor: Skibba, Afshin A., Evans, James R., Hopkins, Steven P., Yoon, H. Richard, Katras, Tony, Kalbfleisch, John H., Rush, Daniel S.
Předmět:
Zdroj: ETSU Faculty Works.
Druh dokumentu: Text
DOI: 10.1016/j.jvs.2015.07.079
Popis: Objective Abdominal aortic aneurysms (AAAs) may rupture at smaller diameters in women than in men, and women may be at higher risk and have poorer outcomes in elective and emergent interventions because of age and comorbidities. Practice guidelines recommending elective AAA repair at >5.5 cm are gender neutral and may not adequately reflect increased risks in women or the potential advantages of elective lower risk endovascular procedures. Methods Patients with a diagnosis of AAA discharged from a single referral hospital during a 14-year period were identified for retrospective analysis. Results A total of 2121 patients with AAAs were studied, 499 women (23.5%) and 1622 men (76.5%). Women were older and had a greater incidence of hypertension, smoking, chronic obstructive pulmonary disease, dyslipidemia, and renal insufficiency. Intact AAAs in 467 women had a mean diameter of 4.4 ± 1.3 cm compared with 1538 men at 5.0 ± 1.4 cm (P
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