Glatiramer Acetate-Induced Lobular Panniculitis and Skin Necrosis

Autor: Watkins, Casey E., Litchfield, John, Youngberg, George, Leicht, Stuart S., Krishnaswamy, Guha
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Zdroj: ETSU Faculty Works.
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Popis: Glatiramer acetate (GA) is a drug that commonly is used for the treatment of relapsing-remitting multiple sclerosis (RRMS). Although it typically is known as a safe and effective therapy, a number of adverse effects associated with GA have been reported in the literature. Local injection-site reactions (LISRs) and mild systemic symptoms are among the most commonly described adverse effects. A review of the literature revealed limited reports of panniculitis as an adverse effect of GA injection and even fewer describing associated skin necrosis. We report a case of GA-induced panniculitis and skin necrosis and discuss the occurrence of panniculitis, necrosis, and lipoatrophy following GA injections.
Databáze: Networked Digital Library of Theses & Dissertations