| Autor: |
Van Orden, L. S., Burke, J. P., Redick, Jan A., Rybarczyk, K. E., Van Orden, Dianna E., Baker, Harriet A., Hartman, B. K. |
| Zdroj: |
ETSU Faculty Works. |
| Druh dokumentu: |
Text |
| DOI: |
10.1016/0028-3908(77)90060-0 |
| Popis: |
Previous biochemical evidence for the localization of phenylethanolamine-N-methyltransferase in adrenal medulla has indicated that this enzyme is soluble, although some workers have reported a significant amount of particulate phenylethanolamine-N-methyltransferase (Joh and Goldstein, 1973). Electron microscopic immunocytochemical study of bovine adrenal medulla has revealed a distinct particulate localization of phenylethanolamine-N-methyltransferase in association with chromaffin granules. It is therefore suggested that some, and possibly most, adrenal phenylethanolamine-N-methyltransferase may be in a particulate form in intact tissue, and that solubilization artifacts during tissue preparation could account in part for the large proportion of soluble phenylethanolarmine-N-methyltransferase reported previously. |
| Databáze: |
Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
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