Established and Emerging Treatments of Skin GvHD
| Autor: | Link-Rachner, Cornelia S., Sockel, Katja, Schuetz, Catharina |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Graft-versus-host disease
cutaneous GvHD acute skin GvHD chronic skin GvHD cell-based therapy targeted therapy GvHD treatment GvHD therapies Graft-versus-Host-Krankheit kutane GvHD akute Haut-GvHD chronische Haut-GvHD zellbasierte Therapie gezielte Therapie GvHD-Behandlung GvHD-Therapien info:eu-repo/classification/ddc/610 ddc:610 |
| Druh dokumentu: | Článek |
| ISSN: | 1664-3224 |
| DOI: | 10.3389/fimmu.2022.838494 |
| Popis: | Graft-versus-host disease (GvHD) of the skin is a severe allo-immune reaction and complication following allogeneic stem cell transplantation. Over the past years, intensive pre-clinical research has led to an improved understanding of the pathophysiology of acute and to a lesser extend chronic GvHD. This has translated into the approval of several new agents for the treatment of both forms of GvHD. This review summarizes the most recent advances in underlying pathomechanisms, clinical trials and newly approved agents for GvHD, with a special focus on skin involvement. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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