Distress in soft‐tissue sarcoma and gastrointestinal stromal tumours patients - Results of a German multicentre observational study (PROSa)

Autor: Eichler, Martin, Hentschel, Leopold, Singer, Susanne, Hornemann, Beate, Hohenberger, Peter, Kasper, Bernd, Andreou, Dimosthenis, Pink, Daniel, Jakob, Jens, Arndt, Karin, Kirchberg, Johanna, Richter, Stephan, Bornhäuser, Martin, Schmitt, Jochen, Schuler, Markus K.
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Druh dokumentu: Článek
ISSN: 1099-1611
DOI: 10.1002/pon.6009
Popis: Objective: Soft tissue sarcomas (STS) and gastrointestinal stromal tumours (GIST) are a group of rare malignant tumours with a high and heterogenous disease burden. As evidence is scarce, we analysed the prevalence of increased emotional distress and identified distress‐associated factors in these patients. - Methods: The PROSa‐study (Burden and medical care of sarcoma) was conducted between 2017 and 2020 in 39 study centres. Cross‐sectional data from adult STS and GIST patients were analysed. Distress was measured with the Patient Health Questionnaire (PHQ‐4). The relation of socioeconomic and clinical factors with distress was explored in adjusted logistic regression models. - Results: Among 897 patients, 17% reported elevated anxiety and 19% reported depression. Unemployed patients (odds ratio [OR] 6.6; 95% CI 2.9–15.0), and those with a disability pension (OR 3.1; 95% CI 1.9–5.0) were more likely to experience distress compared to employed patients. Also, patients with a disability pass had higher odds of increased distress than those without (OR 1.8; 95% CI 1.2–2.7). Lowest distress was observed in patients 2 to
Databáze: Networked Digital Library of Theses & Dissertations
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