Clinical suspicion of spondylodiscitis with equivocal MRI findings: does diffusion-weighted imaging prove helpful here?

Autor: Henkelmann, Jeanette, Bremicker, Kristina, Denecke, Timm, Hoffmann, Karl-Titus, Henkelmann, Ralf, Heyde, Christoph-Eckhard, Sabri, Osama, Purz, Sandra
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Druh dokumentu: Článek
Popis: Background: Despite the high sensitivity of magnetic resonance imaging (MRI), early detection of spondylodiscitis (SpD) remains challenging due to its low specificity. Purpose: To assess the diagnostic value of diffusion-weighted imaging (DWI) in suspected cases of SpD with ambiguous early MRI findings in the differentiation of degenerative disorders (DD). Material and Methods: In this prospective study, 52 patients suspected of having SpD underwent a whole-spine 3-T MRI scan comprising sagittal DWI. Of 58 conspicuous, T2-weighted, signal increased discs, 39 were successfully evaluated using DWI. Apparent diffusion coefficient (ADC) values and ADC maps were blindly analyzed using the region of interest of the conspicuous disc and a normal adjacent reference disc. Intraindividual ratios (conspicuous disc: reference disc) were calculated. Results: All conspicuous discs showed increased absolute ADC values, which did not differ significantly between SpD (n¼22) and DD (n¼17). However, ADC ratio was significantly higher in SpD vs. DD (P
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