| Autor: |
Busch, Catharina, Iglicki, Matias, Okada, Mali, Gabrielle, Pierre-Henry, Cohen, Shai, Mariussi, Miriana, Amphornphruet, Atchara, Cebecki, Zafer, Chaikitmongkol, Voraporn, Couturier, Aude, Fraser-Bell, Samantha, Fung, Adrian T., Iannetta, Danilo, Radecka, Liga, Laíns, Inês, Rodrigues, Tiago M., Lupidi, Marco, Ozimek, Małgorzata, Sala-Puigdollers, Anna, Rehak, Matus, Loewenstein, Anat, Zur, Dinah |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Druh dokumentu: |
Článek |
| ISSN: |
0030-3755 |
| Popis: |
Purpose: The main objective of this study was to investigate the microbiological spectrum of endophthalmitis after anti- VEGF injections and to compare streptococcal with nonstreptococcus- associated cases with regard to baseline characteristics and injection procedure. Methods: Retrospective,international multicenter study of patients with culture-positive endophthalmitis after intravitreal anti-VEGF injection at 17 different retina referral centers. Results: Eighty-three cases with 87 identified pathogens were included. Coagulasenegative staphylococci (59%) and viridans streptococci (15%) were the most frequent pathogens found. The use of postoperative antibiotics and performance of injections in an operating room setting significantly reduced the rate of streptococcus-induced endophthalmitis cases (p = 0.01 for both). Conclusion: We found a statistically significant lower rate of postinjectional local antibiotic therapy and operating room-based procedures among the streptococcus-induced cases compared to cases caused by other organisms. |
| Databáze: |
Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
|
