Effect of L-carnitine supplementation on muscle glycogen utilization and lactate accumulation during cycle exercise

Autor:	Vukovich, Matthew D.
Rok vydání:	1993
Předmět:	Energy metabolism. Exercise Physiological aspects. Lactic acid Metabolism. Muscles Physiology.
Zdroj:	Virtual Press.
Popis:	Two experiments were done to study the effects of L-carnitine supplementation (CNsup) during exercise. EXP 1, examined the effect of CNsup on lipid oxidation and muscle glycogen utilization during submaximal EX. Triglycerides were elevated by a fat feeding (90g fat), 3 h later subjects cycled for 60 min at 70% VO2max (CON). Muscle biopsies were obtained preEX, after 30 and 60 min of EX. Blood samples were taken preEX and every 15 min of EX. Subjects randomly completed two additional trials following 7 and 14 days of CNsup (6 g/day). During one of the trials, subjects received 2000 units of heparin 15 min prior to EX to elevate FFA (CNhep). There were no differences in V02, RER, HR, g of CHO and fat oxidized among the three trials. Serum total acid soluble (TASC) and free carnitine (FC) increased with CNsup (CON, 71.3 ± 2.9; CN, 92.8 ± 5.4; CNhep, 109.8 ± 3.5 mol·g'). Muscle carnitine concentration at rest was unaffected by CNsup. During EX, TASC did not change, FC decreased (p Human Performance Laboratory
Databáze:	Networked Digital Library of Theses & Dissertations
Externí odkaz:	http://cardinalscholar.bsu.edu/handle/handle/181672 http://liblink.bsu.edu/uhtbin/catkey/862276 Zobrazit plný text záznamu