Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model

Autor: Do, Tuan-Minh 1, Capdevila, Cécile 2, Pradier, Laurent 1, Blanchard, Véronique 3, Lopez-Grancha, Mati 1, Schussler, Nathalie 1, Steinmetz, Anke 4, Beninga, Jochen 5, Boulay, Denis 6, Dugay, Philippe 1, Verdier, Patrick 7, Aubin, Nadine 6, Dargazanli, Gihad 8, Chaves, Catarina 1, Genet, Elisabeth 1, Lossouarn, Yves 9, Loux, Christophe 2, Michoux, François 2, Moindrot, Nicolas 1, Chanut, Franck 10, Gury, Thierry 10, Eyquem, Stéphanie 1, Valente, Delphine 9, Bergis, Olivier 6, Rao, Ercole 5, Lesuisse, Dominique 1, ∗
Zdroj: In Molecular Therapy - Methods & Clinical Development 11 December 2020 19:58-77
Databáze: ScienceDirect