Glycodiversification of gentamicins through in vivo glycosyltransferase swapping enabled the creation of novel hybrid aminoglycoside antibiotics with potent activity and low ototoxicity

Autor: Jian, Xinyun, Wang, Cheng, Wu, Shijuan, Sun, Guo, Huang, Chuan, Qiu, Chengbing, Liu, Yuanzheng, Leadlay, Peter F., Liu, Dong, Deng, Zixin, Zhou, Fuling, Sun, Yuhui
Zdroj: In Acta Pharmaceutica Sinica B September 2024 14(9):4149-4163
Databáze: ScienceDirect