Intratumoral administration of mRNA encoding IL-12-based immunocytokines targeting CSF1R and PD-L1 exert potent antitumor effects while restraining systemic exposure to IL-12

Autor: Di Trani, Claudia Augusta, Cirella, Assunta, Arrizabalaga, Leire, Alvarez, Maite, Bella, Ángela, Fernandez-Sendin, Myriam, Russo-Cabrera, Joan Salvador, Gomar, Celia, Ardaiz, Nuria, Teijeira, Alvaro, Bolaños, Elixabet, González-Gomariz, José, Otano, Itziar, Aranda, Fernando, Palencia, Belén, Segués, Aina, Huang, Shuyu, van Duijnhoven, Sander M.J., van Elsas, Andrea, Melero, Ignacio, Berraondo, Pedro
Zdroj: In Molecular Therapy - Nucleic Acids July 2023
Databáze: ScienceDirect