GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors

Autor: Huang, Sijie 1, 2, 3, 12, Xu, Peiyu 1, 2, 12, Shen, Dan-Dan 4, 5, 6, 12, Simon, Icaro A. 7, 8, 11, 12, Mao, Chunyou 4, 5, 6, Tan, Yangxia 1, 2, 3, Zhang, Huibing 4, 5, 6, Harpsøe, Kasper 7, Li, Huadong 1, 2, 3, Zhang, Yumu 1, 2, 3, You, Chongzhao 1, 2, Yu, Xuekui 1, 9, Jiang, Yi 1, 2, Zhang, Yan 4, 5, 6, 10, ∗, Gloriam, David E. 7, 13, ∗∗, Xu, H. Eric 1, 2, 3, 13, 14, ∗∗∗
Zdroj: In Molecular Cell 21 July 2022 82(14):2681-2695
Databáze: ScienceDirect