Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells

Autor: Donohoue, Paul D., Pacesa, Martin, Lau, Elaine, Vidal, Bastien, Irby, Matthew J., Nyer, David B., Rotstein, Tomer, Banh, Lynda, Toh, Mckenzi S., Gibson, Jason, Kohrs, Bryan, Baek, Kevin, Owen, Arthur L.G., Slorach, Euan M., van Overbeek, Megan, Fuller, Christopher K., May, Andrew P., Jinek, Martin, Cameron, Peter
Zdroj: In Molecular Cell 2 September 2021 81(17):3637-3649
Databáze: ScienceDirect