Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction

Autor: Kakiuchi, Y. , Yurube, T. , Kakutani, K. , Takada, T. , Ito, M. , Takeoka, Y. , Kanda, Y. , Miyazaki, S. , Kuroda, R. , Nishida, K.
Zdroj: In Osteoarthritis and Cartilage June 2019 27(6):965-976
Databáze: ScienceDirect