Identification of potent farnesoid X receptor (FXR) antagonist showing favorable PK profile and distribution toward target tissues: Comprehensive understanding of structure-activity relationship of FXR antagonists

Autor: Teno, Naoki a, b, ⁎, Yamashita, Yukiko c, Masuda, Arisa a, Iguchi, Yusuke c, Oda, Keisuke c, Fujimori, Ko d, Hiramoto, Takie a, Nishimaki-Mogami, Tomoko e, Une, Mizuho a, c, Gohda, Keigo f
Zdroj: In Bioorganic & Medicinal Chemistry 1 June 2019 27(11):2220-2227
Databáze: ScienceDirect