Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity

Autor: Beyett, Tyler S., Gan, Xinmin, Reilly, Shannon M., Gomez, Andrew V., Chang, Louise, Tesmer, John J.G., Saltiel, Alan R., Showalter, Hollis D.
Zdroj: In Bioorganic & Medicinal Chemistry 1 November 2018 26(20):5443-5461
Databáze: ScienceDirect