Synthesis and optimization of novel (3S,5R)-5-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)piperidine-3-carboxamides as orally active renin inhibitors

Autor: Mori, Yutaka, Ogawa, Yasuyuki, Mochizuki, Akiyoshi, Nakamura, Yuji, Fujimoto, Teppei, Sugita, Chie, Miyazaki, Shojiro, Tamaki, Kazuhiko, Nagayama, Takahiro, Nagai, Yoko, Inoue, Shin-ichi, Chiba, Katsuyoshi, Nishi, Takahide
Zdroj: In Bioorganic & Medicinal Chemistry 15 September 2013 21(18):5907-5922
Databáze: ScienceDirect
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