Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)

Autor: Lin, Wen-Hsing, Hsu, John T.-A., Hsieh, Shu-Yi, Chen, Chiung-Tong, Song, Jen-Shin, Yen, Shih-Chieh, Hsu, Tsu, Lu, Cheng-Tai, Chen, Chun-Hwa, Chou, Ling-Hui, Yang, Yung-Ning, Chiu, Ching-Hui, Chen, Ching-Ping, Tseng, Ya-Ju, Yen, Kuei-Jung, Yeh, Ching-Fang, Chao, Yu-Sheng, Yeh, Teng-Kuang, Jiaang, Weir-Torn
Zdroj: In Bioorganic & Medicinal Chemistry 1 June 2013 21(11):2856-2867
Databáze: ScienceDirect