2-({6-[(3R)-3-amino-3-methylpiperidine-1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo[3,2-d]pyrimidine-5-yl}methyl)-4-fluorobenzonitrile (DSR-12727): A potent, orally active dipeptidyl peptidase IV inhibitor without mechanism-based inactivation of CYP3A

Autor: Nishio, Yukihiro, Kimura, Hidenori, Sawada, Naoyuki, Sugaru, Eiji, Horiguchi, Masakuni, Ono, Michiko, Furuta, Yudai, Sakai, Mutsuko, Masui, Yumi, Otani, Misato, Hashizuka, Takahiko, Honda, Yayoi, Deguchi, Jiro, Nakagawa, Tsutomu, Nakahira, Hiroyuki
Zdroj: In Bioorganic & Medicinal Chemistry 15 September 2011 19(18):5490-5499
Databáze: ScienceDirect
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