Hypoxic selectivity and solubility—investigating the properties of A-ring substituted nitro seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-ones (nitroCBIs) as hypoxia-activated prodrugs for antitumor therapy
| Autor: | Tercel, Moana, Yang, Shangjin, Atwell, Graham J., Smith, Eileen, Gu, Yongchuan, Anderson, Robert F., Denny, William A., Wilson, William R., Pruijn, Frederik B. |
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| Zdroj: | In Bioorganic & Medicinal Chemistry 15 July 2010 18(14):4997-5006 |
| Databáze: | ScienceDirect |
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