Simultaneous presence of unsaturation and long alkyl chain at [formula omitted] of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies
Autor: | Moroy, Gautier, Denhez, Clément, El Mourabit, Haquima, Toribio, Alix, Dassonville, Alexandra, Decarme, Martine, Renault, Jean-Hugues, Mirand, Catherine, Bellon, Georges, Sapi, Janos, Alix, Alain J.P., Hornebeck, William, Bourguet, Erika |
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Zdroj: | In Bioorganic & Medicinal Chemistry 2007 15(14):4753-4766 |
Databáze: | ScienceDirect |
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