Analysis of human topoisomerase I inhibition and interaction with the cleavage site +1 deoxyguanosine, via in vitro experiments and molecular modeling studies

Autor: Laco, Gary S., Du, Wu, Kohlhagen, Glenda, Sayer, Jane M., Jerina, Donald M., Burke, Thomas G., Curran, Dennis P., Pommier, Yves
Zdroj: In Bioorganic & Medicinal Chemistry 2004 12(19):5225-5235
Databáze: ScienceDirect