Alleviating CYP and hERG liabilities by structure optimization of dihydrofuran-fused tricyclic benzo[d]imidazole series – Potent, selective and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-2
Autor: | Muthukaman, Nagarajan, Deshmukh, Sanjay, Tambe, Macchindra, Pisal, Dnyandeo, Tondlekar, Shital, Shaikh, Mahamadhanif, Sarode, Neelam, Kattige, Vidya G., Sawant, Pooja, Pisat, Monali, Karande, Vikas, Honnegowda, Srinivasa, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Sangana, Ramchandra R., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A. |
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Zdroj: | In Bioorganic & Medicinal Chemistry Letters 15 April 2018 28(7):1211-1218 |
Databáze: | ScienceDirect |
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