Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition

Autor: Lawhorn, Brian G., Tran, Tritin, Hong, Victor S., Morgan, Lisa A., Le, BaoChau T., Harpel, Mark R., Jolivette, Larry, Diaz, Elsie, Schwartz, Benjamin, Gross, Jeffrey W., Tomaszek, Thaddeus, Semus, Simon, Concha, Nestor, Smallwood, Angela, Holt, Dennis A., Kallander, Lara S.
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 November 2017 27(21):4838-4843
Databáze: ScienceDirect