Discovery and optimization of 3-(4-aryl/heteroarylsulfonyl)piperazin-1-yl)-6-(piperidin-1-yl)pyridazines as novel, CNS penetrant pan-muscarinic antagonists
| Autor: | Bender, Aaron M., Weiner, Rebecca L., Luscombe, Vincent B., Ajmera, Sonia, Cho, Hyekyung P., Chang, Sichen, Zhan, Xiaoyan, Rodriguez, Alice L., Niswender, Colleen M., Engers, Darren W., Bridges, Thomas M., Conn, P. Jeffrey, Lindsley, Craig W. |
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| Zdroj: | In Bioorganic & Medicinal Chemistry Letters 1 August 2017 27(15):3576-3581 |
| Databáze: | ScienceDirect |
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