Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice

Autor:	Roecker, Anthony J., Egbertson, Melissa, Jones, Kristen L.G., Gomez, Robert, Kraus, Richard L., Li, Yuxing, Koser, Amy Jo, Urban, Mark O., Klein, Rebecca, Clements, Michelle, Panigel, Jacqueline, Daley, Christopher, Wang, Jixin, Finger, Eleftheria N., Majercak, John, Santarelli, Vincent, Gregan, Irene, Cato, Matthew, Filzen, Tracey, Jovanovska, Aneta, Wang, Ying-Hong, Wang, Deping, Joyce, Leo A., Sherer, Edward C., Peng, Xuanjia, Wang, Xiu, Sun, Haiyan, Coleman, Paul J., Houghton, Andrea K., Layton, Mark E.
Zdroj:	In Bioorganic & Medicinal Chemistry Letters 15 May 2017 27(10):2087-2093
Databáze:	ScienceDirect
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect