Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model

Autor: Han, Wooseok, Menezes, Daniel L., Xu, Yongjin, Knapp, Mark S., Elling, Robert, Burger, Matthew T., Ni, Zhi-Jie, Smith, Aaron, Lan, Jiong, Williams, Teresa E., Verhagen, Joelle, Huh, Kay, Merritt, Hanne, Chan, John, Kaufman, Susan, Voliva, Charles F., Pecchi, Sabina
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 February 2016 26(3):742-746
Databáze: ScienceDirect